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Interleukin-1 Receptor Antagonist Modulates Liver Inflammation and Fibrosis in Mice in a Model-Dependent Manner

Background: Interleukin-1 (IL-1)β and IL-1 receptor antagonist (IL-1Ra) have been proposed as important mediators during chronic liver diseases. We aimed to determine whether the modulation of IL-1β signaling with IL-1Ra impacts on liver fibrosis. Methods: We assessed the effects of IL-1β on human h...

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Detalles Bibliográficos
Autores principales: Meier, Raphael P. H., Meyer, Jeremy, Montanari, Elisa, Lacotte, Stephanie, Balaphas, Alexandre, Muller, Yannick D., Clément, Sophie, Negro, Francesco, Toso, Christian, Morel, Philippe, Buhler, Leo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471711/
https://www.ncbi.nlm.nih.gov/pubmed/30875826
http://dx.doi.org/10.3390/ijms20061295

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