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Interleukin-1 Receptor Antagonist Modulates Liver Inflammation and Fibrosis in Mice in a Model-Dependent Manner
Background: Interleukin-1 (IL-1)β and IL-1 receptor antagonist (IL-1Ra) have been proposed as important mediators during chronic liver diseases. We aimed to determine whether the modulation of IL-1β signaling with IL-1Ra impacts on liver fibrosis. Methods: We assessed the effects of IL-1β on human h...
Autores principales: | Meier, Raphael P. H., Meyer, Jeremy, Montanari, Elisa, Lacotte, Stephanie, Balaphas, Alexandre, Muller, Yannick D., Clément, Sophie, Negro, Francesco, Toso, Christian, Morel, Philippe, Buhler, Leo H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471711/ https://www.ncbi.nlm.nih.gov/pubmed/30875826 http://dx.doi.org/10.3390/ijms20061295 |
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