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Increased Brain-Derived Neurotrophic Factor in Lumbar Dorsal Root Ganglia Contributes to the Enhanced Exercise Pressor Reflex in Heart Failure

An exaggerated exercise pressor reflex (EPR) is associated with excessive sympatho-excitation and exercise intolerance in the chronic heart failure (CHF) state. We hypothesized that brain-derived neurotrophic factor (BDNF) causes the exaggerated EPR via sensitizing muscle mechanosensitive afferents...

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Detalles Bibliográficos
Autores principales:	Schiller, Alicia M., Hong, Juan, Xia, Zhiqiu, Wang, Han-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471760/ https://www.ncbi.nlm.nih.gov/pubmed/30909643 http://dx.doi.org/10.3390/ijms20061480

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