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Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

BACKGROUND: The World Health Organization (WHO) recommends combinations of an artemisinin derivative plus an anti-malarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infections. In Africa, artesunate–mefloquine (ASMQ) is an infrequently used artemisinin-bas...

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Detalles Bibliográficos
Autores principales:	Guidi, Monia, Mercier, Thomas, Aouri, Manel, Decosterd, Laurent A., Csajka, Chantal, Ogutu, Bernhards, Carn, Gwénaëlle, Kiechel, Jean-René
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471806/ https://www.ncbi.nlm.nih.gov/pubmed/30999915 http://dx.doi.org/10.1186/s12936-019-2754-6

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