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Interactions between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl(−)-Transport Shape Activity-Dependent Changes of Intracellular Cl(−) Concentration
The effects of ionotropic γ-aminobutyric acid receptor (GABA-A, GABA(A)) activation depends critically on the Cl(−)-gradient across neuronal membranes. Previous studies demonstrated that the intracellular Cl(−)-concentration ([Cl(−)](i)) is not stable but shows a considerable amount of activity-depe...
Autores principales: | Lombardi, Aniello, Jedlicka, Peter, Luhmann, Heiko J., Kilb, Werner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471822/ https://www.ncbi.nlm.nih.gov/pubmed/30897846 http://dx.doi.org/10.3390/ijms20061416 |
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