Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms

Reactions of a series of 3-oxo-2-arylhydrazonopropanal derivatives with two molar ratio of ammonium acetate afforded a library of tetrasubstituted 2,3,6,7,9-pentaazabicyclo[3.3.1]nona- 3,7-diene derivatives in good to excellent isolated yields. The reaction was activated with triethylamine catalyst...

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Autores principales: Al-Matar, Hamad M., Dawood, Kamal M., Tohamy, Wael M., Shalaby, Mona A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471913/
https://www.ncbi.nlm.nih.gov/pubmed/30897823
http://dx.doi.org/10.3390/molecules24061110
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author Al-Matar, Hamad M.
Dawood, Kamal M.
Tohamy, Wael M.
Shalaby, Mona A.
author_facet Al-Matar, Hamad M.
Dawood, Kamal M.
Tohamy, Wael M.
Shalaby, Mona A.
author_sort Al-Matar, Hamad M.
collection PubMed
description Reactions of a series of 3-oxo-2-arylhydrazonopropanal derivatives with two molar ratio of ammonium acetate afforded a library of tetrasubstituted 2,3,6,7,9-pentaazabicyclo[3.3.1]nona- 3,7-diene derivatives in good to excellent isolated yields. The reaction was activated with triethylamine catalyst under three different heating modes: thermal, ultrasonic and microwave irradiating conditions in ethanol solvent. The structures of the isolated products were fully characterized by spectral and analytical data as well as X-ray single crystal of selected examples.
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spelling pubmed-64719132019-04-26 Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms Al-Matar, Hamad M. Dawood, Kamal M. Tohamy, Wael M. Shalaby, Mona A. Molecules Article Reactions of a series of 3-oxo-2-arylhydrazonopropanal derivatives with two molar ratio of ammonium acetate afforded a library of tetrasubstituted 2,3,6,7,9-pentaazabicyclo[3.3.1]nona- 3,7-diene derivatives in good to excellent isolated yields. The reaction was activated with triethylamine catalyst under three different heating modes: thermal, ultrasonic and microwave irradiating conditions in ethanol solvent. The structures of the isolated products were fully characterized by spectral and analytical data as well as X-ray single crystal of selected examples. MDPI 2019-03-20 /pmc/articles/PMC6471913/ /pubmed/30897823 http://dx.doi.org/10.3390/molecules24061110 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Matar, Hamad M.
Dawood, Kamal M.
Tohamy, Wael M.
Shalaby, Mona A.
Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms
title Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms
title_full Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms
title_fullStr Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms
title_full_unstemmed Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms
title_short Facile Assembling of Novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene Derivatives under Microwave and Ultrasound Platforms
title_sort facile assembling of novel 2,3,6,7,9-pentaazabicyclo- [3.3.1]nona-3,7-diene derivatives under microwave and ultrasound platforms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471913/
https://www.ncbi.nlm.nih.gov/pubmed/30897823
http://dx.doi.org/10.3390/molecules24061110
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