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Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels

The wettability of silicone hydrogel (SiHy) contact lens (CLs) is crucial for the pre-lens tear film stability throughout the day. Therefore, sessile drop and captive bubble setups were used to study the advancing and receding water contact angles (CA) of four SiHy materials: narafilcon A (TE), seno...

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Autores principales: Eftimov, Petar, Yokoi, Norihiko, Peev, Nikola, Georgiev, Georgi As.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471927/
https://www.ncbi.nlm.nih.gov/pubmed/30875896
http://dx.doi.org/10.3390/ijms20061313
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author Eftimov, Petar
Yokoi, Norihiko
Peev, Nikola
Georgiev, Georgi As.
author_facet Eftimov, Petar
Yokoi, Norihiko
Peev, Nikola
Georgiev, Georgi As.
author_sort Eftimov, Petar
collection PubMed
description The wettability of silicone hydrogel (SiHy) contact lens (CLs) is crucial for the pre-lens tear film stability throughout the day. Therefore, sessile drop and captive bubble setups were used to study the advancing and receding water contact angles (CA) of four SiHy materials: narafilcon A (TE), senofilcon A (AOD), stenfilcon A (MD), and delefilcon A (DT). TE and AOD have 48% and 38% water content, respectively, and no surface coating. MD (54% water) implements “smart chemistry” with just 4.4% bulk silicone content, while DT has >80% water at its surface. These SiHy were subjected to continuous blink-like air exposure (10 s)/rehydration (1s) cycles for 0, 1, 2, 3, 4, 6, 8, 10, 12, 14, and 16 h. The advancing CA, which measures the rehydration propensity of the CL surface, proved to be the most sensitive parameter to discriminate between the samples. The order of performance for the entire time scale was DT > MD >> AOD ≥ TE. The extended desiccation/rehydration cycling increased the differences between the CA of DT and MD compared to AOD and TE. This suggests that the low Si surface content and the high surface hydration are major determinants of SiHy wettability.
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spelling pubmed-64719272019-04-26 Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels Eftimov, Petar Yokoi, Norihiko Peev, Nikola Georgiev, Georgi As. Int J Mol Sci Article The wettability of silicone hydrogel (SiHy) contact lens (CLs) is crucial for the pre-lens tear film stability throughout the day. Therefore, sessile drop and captive bubble setups were used to study the advancing and receding water contact angles (CA) of four SiHy materials: narafilcon A (TE), senofilcon A (AOD), stenfilcon A (MD), and delefilcon A (DT). TE and AOD have 48% and 38% water content, respectively, and no surface coating. MD (54% water) implements “smart chemistry” with just 4.4% bulk silicone content, while DT has >80% water at its surface. These SiHy were subjected to continuous blink-like air exposure (10 s)/rehydration (1s) cycles for 0, 1, 2, 3, 4, 6, 8, 10, 12, 14, and 16 h. The advancing CA, which measures the rehydration propensity of the CL surface, proved to be the most sensitive parameter to discriminate between the samples. The order of performance for the entire time scale was DT > MD >> AOD ≥ TE. The extended desiccation/rehydration cycling increased the differences between the CA of DT and MD compared to AOD and TE. This suggests that the low Si surface content and the high surface hydration are major determinants of SiHy wettability. MDPI 2019-03-15 /pmc/articles/PMC6471927/ /pubmed/30875896 http://dx.doi.org/10.3390/ijms20061313 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Eftimov, Petar
Yokoi, Norihiko
Peev, Nikola
Georgiev, Georgi As.
Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
title Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
title_full Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
title_fullStr Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
title_full_unstemmed Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
title_short Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
title_sort impact of air exposure time on the water contact angles of daily disposable silicone hydrogels
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471927/
https://www.ncbi.nlm.nih.gov/pubmed/30875896
http://dx.doi.org/10.3390/ijms20061313
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