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Targeting the ERK Signaling Pathway in Melanoma

The discovery of the role of the RAS/RAF/MEK/ERK pathway in melanomagenesis and its progression have opened a new era in the treatment of this tumor. Vemurafenib was the first specific kinase inhibitor approved for therapy of advanced melanomas harboring BRAF-activating mutations, followed by dabraf...

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Detalles Bibliográficos
Autores principales:	Savoia, Paola, Fava, Paolo, Casoni, Filippo, Cremona, Ottavio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472057/ https://www.ncbi.nlm.nih.gov/pubmed/30934534 http://dx.doi.org/10.3390/ijms20061483

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