Balanced Reciprocal Translocation: Multiple Chromosome Rearrangements in an Infertile Female

Double reciprocal translocations and triple-balanced reciprocal translocations multiple chromosome rearrangements are very rare events in the phenotypically normal individuals. Chromosome analysis with 500-band resolution was performed and analyzed in an infertile woman. Her karyotype revealed 46,XX...

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Detalles Bibliográficos
Autores principales: Gupta, Neelam, Dalvi, Rupa, Koppaka, Neeraja, Mandava, Swarna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472205/
https://www.ncbi.nlm.nih.gov/pubmed/31007471
http://dx.doi.org/10.4103/jhrs.JHRS_122_18
Descripción
Sumario:Double reciprocal translocations and triple-balanced reciprocal translocations multiple chromosome rearrangements are very rare events in the phenotypically normal individuals. Chromosome analysis with 500-band resolution was performed and analyzed in an infertile woman. Her karyotype revealed 46,XX, t(1;3) (q44;p11), t(2;14) (q11.2;q13), t(9;11) (p22;p15) pattern in all the metaphases. To the best of our knowledge, this is the first case of triple-balanced reciprocal translocations in an infertile woman.

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