SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation

SIRT2, a member of the sirtuin family, has been recently shown to exert important effects on mitosis and/or metabolism. However, its roles in oocyte maturation have not been fully clarified. In this study, SIRT2, located in the cytoplasm and nucleus, was found in abundance in the meiotic stage, and...

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Detalles Bibliográficos
Autores principales: Xu, Dejun, Wu, Lin, Jiang, Xiaohan, Yang, Li, Cheng, Jianyong, Chen, Huali, Hua, Rongmao, Geng, Guoxia, Yang, Lulu, Li, Qingwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472277/
https://www.ncbi.nlm.nih.gov/pubmed/30889926
http://dx.doi.org/10.3390/ijms20061365

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