L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction

L-amino acid transporters (LATs) play key roles in human physiology and are implicated in several human pathologies. LATs are asymmetric amino acid exchangers where the low apparent affinity cytoplasmic side controls the exchange of substrates with high apparent affinity on the extracellular side. H...

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Detalles Bibliográficos
Autores principales: Errasti-Murugarren, Ekaitz, Fort, Joana, Bartoccioni, Paola, Díaz, Lucía, Pardon, Els, Carpena, Xavier, Espino-Guarch, Meritxell, Zorzano, Antonio, Ziegler, Christine, Steyaert, Jan, Fernández-Recio, Juan, Fita, Ignacio, Palacín, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472337/
https://www.ncbi.nlm.nih.gov/pubmed/31000719
http://dx.doi.org/10.1038/s41467-019-09837-z

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