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Self-organization of Plk4 regulates symmetry breaking in centriole duplication
During centriole duplication, a single daughter centriole is formed next to the mother centriole. The molecular mechanism that determines a single duplication site remains a long-standing question. Here, we show that intrinsic self-organization of Plk4 is implicated in symmetry breaking in the proce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472344/ https://www.ncbi.nlm.nih.gov/pubmed/31000710 http://dx.doi.org/10.1038/s41467-019-09847-x |