Assembly of functionalized silk together with cells to obtain proliferative 3D cultures integrated in a network of ECM-like microfibers

Tissues are built of cells integrated in an extracellular matrix (ECM) which provides a three-dimensional (3D) microfiber network with specific sites for cell anchorage. By genetic engineering, motifs from the ECM can be functionally fused to recombinant silk proteins. Such a silk protein, FN-silk,...

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Detalles Bibliográficos
Autores principales: Johansson, Ulrika, Widhe, Mona, Shalaly, Nancy Dekki, Arregui, Irene Linares, Nilebäck, Linnea, Tasiopoulos, Christos Panagiotis, Åstrand, Carolina, Berggren, Per-Olof, Gasser, Christian, Hedhammar, My
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472362/
https://www.ncbi.nlm.nih.gov/pubmed/31000733
http://dx.doi.org/10.1038/s41598-019-42541-y

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