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RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas
Aldosterone producing adenomas (APAs) occur in the adrenal glands of around 30% of patients with primary aldosteronism, the most common form of secondary hypertension. Somatic mutations in KCNJ5, ATP1A1, ATP2B3, CACNA1D and CTNNB1 have been described in ~60% of these tumours. We subjected 15 aldoste...
Autores principales: | Backman, Samuel, Åkerström, Tobias, Maharjan, Rajani, Cupisti, Kenko, Willenberg, Holger S., Hellman, Per, Björklund, Peyman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472367/ https://www.ncbi.nlm.nih.gov/pubmed/31000732 http://dx.doi.org/10.1038/s41598-019-41525-2 |
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