Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

The fields of toxicology and chemical risk assessment seek to reduce, and eventually replace, the use of animals for the prediction of toxicity in humans. In this context, physiologically based kinetic (PBK) modelling based on in vitro and in silico kinetic data has the potential to a play significa...

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Detalles Bibliográficos
Autores principales: Paini, A., Leonard, J.A., Joossens, E., Bessems, J.G.M., Desalegn, A., Dorne, J.L., Gosling, J.P., Heringa, M.B., Klaric, M., Kliment, T., Kramer, N.I., Loizou, G., Louisse, J., Lumen, A., Madden, J.C., Patterson, E.A., Proença, S., Punt, A., Setzer, R.W., Suciu, N., Troutman, J., Yoon, M., Worth, A., Tan, Y.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472623/
https://www.ncbi.nlm.nih.gov/pubmed/31008414
http://dx.doi.org/10.1016/j.comtox.2018.11.002

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