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Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition

Selective inhibition describes the stopping of an action while other actions are further executed. It can be differentiated between two strategies to stop selectively: the fast but global stop all, then discriminate strategy and the slower but more selective first discriminate, then stop strategy. I...

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Autores principales: Antons, Stephanie, Boecker, Maren, Gauggel, Siegfried, Gordi, Vera Michaela, Patel, Harshal Jayeshkumar, Binkofski, Ferdinand, Drueke, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472739/
https://www.ncbi.nlm.nih.gov/pubmed/30998717
http://dx.doi.org/10.1371/journal.pone.0214652
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author Antons, Stephanie
Boecker, Maren
Gauggel, Siegfried
Gordi, Vera Michaela
Patel, Harshal Jayeshkumar
Binkofski, Ferdinand
Drueke, Barbara
author_facet Antons, Stephanie
Boecker, Maren
Gauggel, Siegfried
Gordi, Vera Michaela
Patel, Harshal Jayeshkumar
Binkofski, Ferdinand
Drueke, Barbara
author_sort Antons, Stephanie
collection PubMed
description Selective inhibition describes the stopping of an action while other actions are further executed. It can be differentiated between two strategies to stop selectively: the fast but global stop all, then discriminate strategy and the slower but more selective first discriminate, then stop strategy. It is assumed that the first discriminate, then stop strategy is especially used when information regarding which action might have to be stopped is already available beforehand. Moreover, it is supposed that both strategies differ in matters of basal ganglia pathways used for their execution. Aim of the present study was to investigate the use of the two strategies in situations requiring selective changing of an action. Eighteen healthy male participants performed a selective stop-change task with informative and uninformative cues during fMRI. Behavioral results show that informative cues led to a benefit in both inhibition times and selectivity. FMRI data revealed that the same cortico-subcortical pathway was used with informative and uninformative cues. Behavioral and neuronal results indicate that participants used the first discriminate, then stop strategy for selective inhibition irrespective of the amount of previously available information. Moreover, the neural activity data indicate that the benefit in the informed condition was produced by an efficient preparation for the concrete change process. Possible factors that might affect which strategy is used for selective stopping are the level of previously available information (foreknowledge) and the experimental set-up, as e.g. task complexity.
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spelling pubmed-64727392019-05-03 Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition Antons, Stephanie Boecker, Maren Gauggel, Siegfried Gordi, Vera Michaela Patel, Harshal Jayeshkumar Binkofski, Ferdinand Drueke, Barbara PLoS One Research Article Selective inhibition describes the stopping of an action while other actions are further executed. It can be differentiated between two strategies to stop selectively: the fast but global stop all, then discriminate strategy and the slower but more selective first discriminate, then stop strategy. It is assumed that the first discriminate, then stop strategy is especially used when information regarding which action might have to be stopped is already available beforehand. Moreover, it is supposed that both strategies differ in matters of basal ganglia pathways used for their execution. Aim of the present study was to investigate the use of the two strategies in situations requiring selective changing of an action. Eighteen healthy male participants performed a selective stop-change task with informative and uninformative cues during fMRI. Behavioral results show that informative cues led to a benefit in both inhibition times and selectivity. FMRI data revealed that the same cortico-subcortical pathway was used with informative and uninformative cues. Behavioral and neuronal results indicate that participants used the first discriminate, then stop strategy for selective inhibition irrespective of the amount of previously available information. Moreover, the neural activity data indicate that the benefit in the informed condition was produced by an efficient preparation for the concrete change process. Possible factors that might affect which strategy is used for selective stopping are the level of previously available information (foreknowledge) and the experimental set-up, as e.g. task complexity. Public Library of Science 2019-04-18 /pmc/articles/PMC6472739/ /pubmed/30998717 http://dx.doi.org/10.1371/journal.pone.0214652 Text en © 2019 Antons et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Antons, Stephanie
Boecker, Maren
Gauggel, Siegfried
Gordi, Vera Michaela
Patel, Harshal Jayeshkumar
Binkofski, Ferdinand
Drueke, Barbara
Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition
title Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition
title_full Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition
title_fullStr Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition
title_full_unstemmed Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition
title_short Strategies of selective changing: Preparatory neural processes seem to be responsible for differences in complex inhibition
title_sort strategies of selective changing: preparatory neural processes seem to be responsible for differences in complex inhibition
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472739/
https://www.ncbi.nlm.nih.gov/pubmed/30998717
http://dx.doi.org/10.1371/journal.pone.0214652
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