The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection

Host innate immune defences play a critical role in restricting the intracellular propagation and pathogenesis of invading viral pathogens. Here we show that the histone H3.3 chaperone HIRA (histone cell cycle regulator) associates with promyelocytic leukaemia nuclear bodies (PML-NBs) to stimulate t...

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Detalles Bibliográficos
Autores principales: McFarlane, Steven, Orr, Anne, Roberts, Ashley P. E., Conn, Kristen L., Iliev, Victor, Loney, Colin, da Silva Filipe, Ana, Smollett, Katherine, Gu, Quan, Robertson, Neil, Adams, Peter D., Rai, Taranjit Singh, Boutell, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472835/
https://www.ncbi.nlm.nih.gov/pubmed/30901352
http://dx.doi.org/10.1371/journal.ppat.1007667

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