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Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection

OBJECTIVE: To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection. MATERIALS AND METHODS: We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 20...

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Autores principales: Adôrno, Isa Félix, Tibana, Tiago Kojun, Santos, Rômulo Florêncio Tristão, Leão, Victor Machado Mendes, Brustoloni, Yvone Maia, Silva, Pedro Augusto Ignácio, Ferreira, Marco Antônio, Nunes, Thiago Franchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472857/
https://www.ncbi.nlm.nih.gov/pubmed/31019335
http://dx.doi.org/10.1590/0100-3984.2018.0030
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author Adôrno, Isa Félix
Tibana, Tiago Kojun
Santos, Rômulo Florêncio Tristão
Leão, Victor Machado Mendes
Brustoloni, Yvone Maia
Silva, Pedro Augusto Ignácio
Ferreira, Marco Antônio
Nunes, Thiago Franchi
author_facet Adôrno, Isa Félix
Tibana, Tiago Kojun
Santos, Rômulo Florêncio Tristão
Leão, Victor Machado Mendes
Brustoloni, Yvone Maia
Silva, Pedro Augusto Ignácio
Ferreira, Marco Antônio
Nunes, Thiago Franchi
author_sort Adôrno, Isa Félix
collection PubMed
description OBJECTIVE: To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection. MATERIALS AND METHODS: We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 2016. The mean age of the patients was 14 months (range, 2-89 months). The diagnosis was established on the basis of clinical and radiographic criteria, and the virus was detected by polymerase chain reaction. The radiographic findings were categorized by type/pattern of opacity and by lung zone. The patients were divided into two groups: those not requiring ventilatory support; and those requiring ventilatory support or evolving to death. RESULTS: The abnormality most often seen on chest X-rays was that of peribronchovascular opacities, the majority of which affected less than 25% of the lung, the involvement being bilateral and asymmetric. The lung zone most frequently involved was the middle third, with central and peripheral distribution, without pleural effusion. There was a statistically significant difference between the groups in terms of the symmetry of pulmonary involvement, asymmetric findings predominating in the group that required ventilatory support (p = 0.029). CONCLUSION: In pediatric patients with H1N1 virus infection, the main alterations on the initial chest X-rays are peribronchovascular opacities, nonspecific alveolar opacities, and consolidations. Although the definitive diagnosis of H1N1 virus infection cannot be made on the basis of imaging characteristics alone, using a combination of clinical and radiographic findings can substantially improve the diagnostic accuracy.
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spelling pubmed-64728572019-04-24 Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection Adôrno, Isa Félix Tibana, Tiago Kojun Santos, Rômulo Florêncio Tristão Leão, Victor Machado Mendes Brustoloni, Yvone Maia Silva, Pedro Augusto Ignácio Ferreira, Marco Antônio Nunes, Thiago Franchi Radiol Bras Original Article OBJECTIVE: To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection. MATERIALS AND METHODS: We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 2016. The mean age of the patients was 14 months (range, 2-89 months). The diagnosis was established on the basis of clinical and radiographic criteria, and the virus was detected by polymerase chain reaction. The radiographic findings were categorized by type/pattern of opacity and by lung zone. The patients were divided into two groups: those not requiring ventilatory support; and those requiring ventilatory support or evolving to death. RESULTS: The abnormality most often seen on chest X-rays was that of peribronchovascular opacities, the majority of which affected less than 25% of the lung, the involvement being bilateral and asymmetric. The lung zone most frequently involved was the middle third, with central and peripheral distribution, without pleural effusion. There was a statistically significant difference between the groups in terms of the symmetry of pulmonary involvement, asymmetric findings predominating in the group that required ventilatory support (p = 0.029). CONCLUSION: In pediatric patients with H1N1 virus infection, the main alterations on the initial chest X-rays are peribronchovascular opacities, nonspecific alveolar opacities, and consolidations. Although the definitive diagnosis of H1N1 virus infection cannot be made on the basis of imaging characteristics alone, using a combination of clinical and radiographic findings can substantially improve the diagnostic accuracy. Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2019 /pmc/articles/PMC6472857/ /pubmed/31019335 http://dx.doi.org/10.1590/0100-3984.2018.0030 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Adôrno, Isa Félix
Tibana, Tiago Kojun
Santos, Rômulo Florêncio Tristão
Leão, Victor Machado Mendes
Brustoloni, Yvone Maia
Silva, Pedro Augusto Ignácio
Ferreira, Marco Antônio
Nunes, Thiago Franchi
Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection
title Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection
title_full Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection
title_fullStr Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection
title_full_unstemmed Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection
title_short Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection
title_sort initial chest x-ray findings in pediatric patients diagnosed with h1n1 virus infection
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472857/
https://www.ncbi.nlm.nih.gov/pubmed/31019335
http://dx.doi.org/10.1590/0100-3984.2018.0030
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