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Qa-1-Restricted CD8(+) T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection
The role of non-classical T cells during viral infection remains poorly understood. Using the well-established murine model of CMV infection (MCMV) and mice deficient in MHC class Ia molecules, we found that non-classical CD8(+) T cells robustly expand after MCMV challenge, become highly activated e...
Autores principales: | Anderson, Courtney K., Reilly, Emma C., Lee, Angus Y., Brossay, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472915/ https://www.ncbi.nlm.nih.gov/pubmed/30970256 http://dx.doi.org/10.1016/j.celrep.2019.03.059 |
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