Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection causes an exacerbation are poorly understood. By using systems-scale network analysis, we identify repertoires of cellular transcriptional path...

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Detalles Bibliográficos
Autores principales: Altman, Matthew C., Gill, Michelle A., Whalen, Elizabeth, Babineau, Denise C., Shao, Baomei, Liu, Andrew H., Jepson, Brett, Gruchalla, Rebecca S., O’Connor, George T., Pongracic, Jacqueline A., Kercsmar, Carolyn M., Khurana Hershey, Gurjit K., Zoratti, Edward M., Johnson, Christine C., Teach, Stephen J., Kattan, Meyer, Bacharier, Leonard B., Beigelman, Avraham, Sigelman, Steve M., Presnell, Scott, Gern, James E., Gergen, Peter J., Wheatley, Lisa M., Togias, Alkis, Busse, William W., Jackson, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472965/
https://www.ncbi.nlm.nih.gov/pubmed/30962590
http://dx.doi.org/10.1038/s41590-019-0347-8

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