Extension of Maximal Lifespan and High Bone Marrow Chimerism After Nonmyeloablative Syngeneic Transplantation of Bone Marrow From Young to Old Mice

The goal of this work was to determine the effect of nonablative syngeneic transplantation of young bone marrow (BM) to laboratory animals (mice) of advanced age upon maximum duration of their lifespan. To do this, transplantation of 100 million nucleated cells from BM of young syngeneic donors to a...

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Detalles Bibliográficos
Autores principales: Kovina, Marina V., Karnaukhov, Alexey V., Krasheninnikov, Mikhail E., Kovin, Artem L., Gazheev, Sarul T., Sergievich, Larisa A., Karnaukhova, Elena V., Bogdanenko, Elena V., Balyasin, Maxim V., Khodarovich, Yury M., Dyuzheva, Tatyana G., Lyundup, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473025/
https://www.ncbi.nlm.nih.gov/pubmed/31031800
http://dx.doi.org/10.3389/fgene.2019.00310

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