CD4(+) T Cell-Dependent Macrophage Activation Modulates Sustained PS Exposure on Intracellular Amastigotes of Leishmania amazonensis

Leishmania amazonensis amastigotes can make use of surface-exposed phosphatidylserine (PS) molecules to promote infection and non-classical activation of macrophages (MΦ), leading to uncontrolled intracellular proliferation of the parasites. This mechanism was quoted as apoptotic mimicry. Moreover,...

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Detalles Bibliográficos
Autores principales: Wanderley, Joao Luiz Mendes, Deolindo, Poliana, Carlsen, Eric, Portugal, Arieli Bernardo, DaMatta, Renato Augusto, Barcinski, Marcello Andre, Soong, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473175/
https://www.ncbi.nlm.nih.gov/pubmed/31032234
http://dx.doi.org/10.3389/fcimb.2019.00105

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