Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection

Autophagy can either antagonize or promote intracellular bacterial growth, depending on the pathogen. Here, we investigated the role of autophagy during a pulmonary infection with the obligate intracellular pathogen, Chlamydia pneumoniae (CP). In mouse embryonic fibroblasts (MEFs) or macrophages, de...

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Detalles Bibliográficos
Autores principales: Crother, Timothy R., Porritt, Rebecca A., Dagvadorj, Jargalsaikhan, Tumurkhuu, Gantsetseg, Slepenkin, Anatoly V., Peterson, Ellena M., Chen, Shuang, Shimada, Kenichi, Arditi, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473188/
https://www.ncbi.nlm.nih.gov/pubmed/31031755
http://dx.doi.org/10.3389/fimmu.2019.00754

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