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NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals
Defects in counterregulatory mechanisms contribute to amplify the detrimental inflammatory response leading to the pathologic process occurring in the gut of patients with Crohn’s disease (CD) and ulcerative colitis (UC), the major inflammatory bowel diseases (IBDs), in human beings. One such mechan...
Autores principales: | Marafini, Irene, Di Fusco, Davide, Dinallo, Vincenzo, Franzè, Eleonora, Stolfi, Carmine, Sica, Giuseppe, Monteleone, Giovanni, Monteleone, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473199/ https://www.ncbi.nlm.nih.gov/pubmed/31031628 http://dx.doi.org/10.3389/fphar.2019.00380 |
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