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Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan

The mitochondrial free radical theory of aging (mFRTA) proposes that accumulation of oxidative damage to macromolecules in mitochondria is a causative mechanism for aging. Accumulation of mitochondrial DNA (mtDNA) damage may be of particular interest in this context. While there is evidence for age-...

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Detalles Bibliográficos
Autores principales:	Ng, Li Fang, Ng, Li Theng, van Breugel, Michiel, Halliwell, Barry, Gruber, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473201/ https://www.ncbi.nlm.nih.gov/pubmed/31031801 http://dx.doi.org/10.3389/fgene.2019.00311

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