Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate

Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the init...

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Autores principales: Yuhana, Yazli, Tanganuchitcharnchai, Ampai, Sujariyakul, Pimpan, Sonthayanon, Piengchan, Chotivanich, Kesinee, Paris, Daniel H., Pukrittayakamee, Sasithon, Blacksell, Stuart D., Hanboonkunupakarn, Borimas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473229/
https://www.ncbi.nlm.nih.gov/pubmed/30708964
http://dx.doi.org/10.3390/tropicalmed4010023
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author Yuhana, Yazli
Tanganuchitcharnchai, Ampai
Sujariyakul, Pimpan
Sonthayanon, Piengchan
Chotivanich, Kesinee
Paris, Daniel H.
Pukrittayakamee, Sasithon
Blacksell, Stuart D.
Hanboonkunupakarn, Borimas
author_facet Yuhana, Yazli
Tanganuchitcharnchai, Ampai
Sujariyakul, Pimpan
Sonthayanon, Piengchan
Chotivanich, Kesinee
Paris, Daniel H.
Pukrittayakamee, Sasithon
Blacksell, Stuart D.
Hanboonkunupakarn, Borimas
author_sort Yuhana, Yazli
collection PubMed
description Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the initial empirical treatment for leptospirosis, he showed a rapid response to doxycycline when murine typhus was diagnosed later. This case highlights the importance of considering murine typhus as a diagnostic in cases of acute febrile illness in urban and sub-urban areas, such as that of in Peninsular Malaysia.
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spelling pubmed-64732292019-04-29 Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate Yuhana, Yazli Tanganuchitcharnchai, Ampai Sujariyakul, Pimpan Sonthayanon, Piengchan Chotivanich, Kesinee Paris, Daniel H. Pukrittayakamee, Sasithon Blacksell, Stuart D. Hanboonkunupakarn, Borimas Trop Med Infect Dis Case Report Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the initial empirical treatment for leptospirosis, he showed a rapid response to doxycycline when murine typhus was diagnosed later. This case highlights the importance of considering murine typhus as a diagnostic in cases of acute febrile illness in urban and sub-urban areas, such as that of in Peninsular Malaysia. MDPI 2019-01-31 /pmc/articles/PMC6473229/ /pubmed/30708964 http://dx.doi.org/10.3390/tropicalmed4010023 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Yuhana, Yazli
Tanganuchitcharnchai, Ampai
Sujariyakul, Pimpan
Sonthayanon, Piengchan
Chotivanich, Kesinee
Paris, Daniel H.
Pukrittayakamee, Sasithon
Blacksell, Stuart D.
Hanboonkunupakarn, Borimas
Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate
title Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate
title_full Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate
title_fullStr Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate
title_full_unstemmed Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate
title_short Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate
title_sort diagnosis of murine typhus by serology in peninsular malaysia: a case report where rickettsial illnesses, leptospirosis and dengue co-circulate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473229/
https://www.ncbi.nlm.nih.gov/pubmed/30708964
http://dx.doi.org/10.3390/tropicalmed4010023
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