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A Potential Therapy Using Engineered Stem Cells Prevented Malignant Melanoma in Cellular and Xenograft Mouse Models

PURPOSE: In the present study, human neural stem cells (hNSCs) with tumor-tropic behavior were used as drug delivery vehicle to selectively target melanoma. A hNSC line (HB1.F3) was transduced into two types: one expressed only the cytosine deaminase (CD) gene (HB1.F3. CD) and the other expressed bo...

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Detalles Bibliográficos
Autores principales: Heo, Jae-Rim, Hwang, Kyung-A, Kim, Seung U., Choi, Kyung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473263/
https://www.ncbi.nlm.nih.gov/pubmed/30213181
http://dx.doi.org/10.4143/crt.2018.364