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Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria

Background: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods:...

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Autores principales: Halvorsen, Kjell H., Kucukcelik, Sinan, Garcia, Beate H., Svendsen, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473407/
https://www.ncbi.nlm.nih.gov/pubmed/30841495
http://dx.doi.org/10.3390/pharmacy7010026
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author Halvorsen, Kjell H.
Kucukcelik, Sinan
Garcia, Beate H.
Svendsen, Kristian
author_facet Halvorsen, Kjell H.
Kucukcelik, Sinan
Garcia, Beate H.
Svendsen, Kristian
author_sort Halvorsen, Kjell H.
collection PubMed
description Background: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods: A cross-sectional study of long-term care residents from six nursing homes. Data was collected from medical records. We identified PIMs by applying the NORGEP-NH criteria. We conducted a Poisson regression analysis to investigate the association between the number of PIMs and sex, age, number of medicines, and study location. Results: We included 103 (18.4%) of 559 residents (68.0% women; mean age 83.2 years, mean number of daily used medicines 7.2 (SD = 3.6)). We identified PIMs in 56% of the residents (mean number = 1.10, SD = 1.26). In adjusted analyses, residents ≥80 years had 0.43 fewer PIMs compared to residents <80 years (p < 0.05). Residents using 4–6, 7–9, and 10+ medicines had on average 0.73, 1.06, and 2.11 more PIMs compared to residents using 0–3 medicines (p < 0.001), respectively. Conclusion: PIM use is prevalent among nursing home residents and is significantly associated with age and number of medicines. Our findings suggest a modest decrease in residents using PIMs compared to previous studies. Nevertheless, prescribing quality in nursing home residents in both urban and rural areas is still of great concern.
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spelling pubmed-64734072019-04-29 Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria Halvorsen, Kjell H. Kucukcelik, Sinan Garcia, Beate H. Svendsen, Kristian Pharmacy (Basel) Article Background: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods: A cross-sectional study of long-term care residents from six nursing homes. Data was collected from medical records. We identified PIMs by applying the NORGEP-NH criteria. We conducted a Poisson regression analysis to investigate the association between the number of PIMs and sex, age, number of medicines, and study location. Results: We included 103 (18.4%) of 559 residents (68.0% women; mean age 83.2 years, mean number of daily used medicines 7.2 (SD = 3.6)). We identified PIMs in 56% of the residents (mean number = 1.10, SD = 1.26). In adjusted analyses, residents ≥80 years had 0.43 fewer PIMs compared to residents <80 years (p < 0.05). Residents using 4–6, 7–9, and 10+ medicines had on average 0.73, 1.06, and 2.11 more PIMs compared to residents using 0–3 medicines (p < 0.001), respectively. Conclusion: PIM use is prevalent among nursing home residents and is significantly associated with age and number of medicines. Our findings suggest a modest decrease in residents using PIMs compared to previous studies. Nevertheless, prescribing quality in nursing home residents in both urban and rural areas is still of great concern. MDPI 2019-03-05 /pmc/articles/PMC6473407/ /pubmed/30841495 http://dx.doi.org/10.3390/pharmacy7010026 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Halvorsen, Kjell H.
Kucukcelik, Sinan
Garcia, Beate H.
Svendsen, Kristian
Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_full Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_fullStr Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_full_unstemmed Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_short Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_sort assessing potentially inappropriate medications in nursing home residents by norgep-nh criteria
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473407/
https://www.ncbi.nlm.nih.gov/pubmed/30841495
http://dx.doi.org/10.3390/pharmacy7010026
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