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Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’

Melioidosis is a frequently fatal infectious disease caused by the Gram negative bacillus Burkholderia pseudomallei. Although it was originally discovered in Myanmar, the disease disappeared from sight for many decades. This study focuses on detection of B. pseudomallei in soil in selected sampling...

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Autores principales: Win, Tun Tun, Su, Khine Khine, Than, Aye Min, Htut, Zaw Min, Pyar, Khin Phyu, Ashley, Elizabeth A., Dance, David A. B., Tun, Kyaw Myo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473437/
https://www.ncbi.nlm.nih.gov/pubmed/30621177
http://dx.doi.org/10.3390/tropicalmed4010008
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author Win, Tun Tun
Su, Khine Khine
Than, Aye Min
Htut, Zaw Min
Pyar, Khin Phyu
Ashley, Elizabeth A.
Dance, David A. B.
Tun, Kyaw Myo
author_facet Win, Tun Tun
Su, Khine Khine
Than, Aye Min
Htut, Zaw Min
Pyar, Khin Phyu
Ashley, Elizabeth A.
Dance, David A. B.
Tun, Kyaw Myo
author_sort Win, Tun Tun
collection PubMed
description Melioidosis is a frequently fatal infectious disease caused by the Gram negative bacillus Burkholderia pseudomallei. Although it was originally discovered in Myanmar, the disease disappeared from sight for many decades. This study focuses on detection of B. pseudomallei in soil in selected sampling sites in an attempt to start to fill the gaps in the current status of our knowledge of the geographical distribution of B. pseudomallei in soil in Myanmar. This cross-sectional study consists of 400 soil samples from 10 selected study townships from two major paddy growing regions. Bacterial isolation was done using a simplified method for the isolation of Burkholderia pseudomallei from soil. In this study, only 1% (4/400) of soil samples were found to be positive; two of four were found at 90 cm depth and another two positive samples were found at 30 cm and 60 cm. This survey has confirmed the presence of environmental B. pseudomallei in Myanmar indicating that the conditions are in place for melioidosis acquisition.
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spelling pubmed-64734372019-04-29 Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’ Win, Tun Tun Su, Khine Khine Than, Aye Min Htut, Zaw Min Pyar, Khin Phyu Ashley, Elizabeth A. Dance, David A. B. Tun, Kyaw Myo Trop Med Infect Dis Article Melioidosis is a frequently fatal infectious disease caused by the Gram negative bacillus Burkholderia pseudomallei. Although it was originally discovered in Myanmar, the disease disappeared from sight for many decades. This study focuses on detection of B. pseudomallei in soil in selected sampling sites in an attempt to start to fill the gaps in the current status of our knowledge of the geographical distribution of B. pseudomallei in soil in Myanmar. This cross-sectional study consists of 400 soil samples from 10 selected study townships from two major paddy growing regions. Bacterial isolation was done using a simplified method for the isolation of Burkholderia pseudomallei from soil. In this study, only 1% (4/400) of soil samples were found to be positive; two of four were found at 90 cm depth and another two positive samples were found at 30 cm and 60 cm. This survey has confirmed the presence of environmental B. pseudomallei in Myanmar indicating that the conditions are in place for melioidosis acquisition. MDPI 2019-01-04 /pmc/articles/PMC6473437/ /pubmed/30621177 http://dx.doi.org/10.3390/tropicalmed4010008 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Win, Tun Tun
Su, Khine Khine
Than, Aye Min
Htut, Zaw Min
Pyar, Khin Phyu
Ashley, Elizabeth A.
Dance, David A. B.
Tun, Kyaw Myo
Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’
title Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’
title_full Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’
title_fullStr Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’
title_full_unstemmed Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’
title_short Presence of Burkholderia pseudomallei in the ‘Granary of Myanmar’
title_sort presence of burkholderia pseudomallei in the ‘granary of myanmar’
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473437/
https://www.ncbi.nlm.nih.gov/pubmed/30621177
http://dx.doi.org/10.3390/tropicalmed4010008
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