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P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages
Chikungunya virus (CHIKV), a mosquito-borne Alphavirus, is endemic in different parts of the globe. The host macrophages are identified as the major cellular reservoirs of CHIKV during infection and this virus triggers robust TNF production in the host macrophages, which might be a key mediator of v...
Autores principales: | Nayak, Tapas Kumar, Mamidi, Prabhudutta, Sahoo, Subhransu Sekhar, Kumar, P. Sanjai, Mahish, Chandan, Chatterjee, Sanchari, Subudhi, Bharat Bhusan, Chattopadhyay, Soma, Chattopadhyay, Subhasis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473476/ https://www.ncbi.nlm.nih.gov/pubmed/31031770 http://dx.doi.org/10.3389/fimmu.2019.00786 |
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