Cargando…

Proteomic Profiling of Primary Human Acute Myeloid Leukemia Cells Does Not Reflect Their Constitutive Release of Soluble Mediators

Acute myeloid leukemia (AML) is a heterogeneous disease, and communication between leukemic cells and their neighboring leukemia-supporting normal cells is involved in leukemogenesis. The bone marrow cytokine network is therefore important, and the mediator release profile seems more important than...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aasebø, Elise, Hernandez-Valladares, Maria, Selheim, Frode, Berven, Frode S., Brenner, Annette K., Bruserud, Øystein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473519/ https://www.ncbi.nlm.nih.gov/pubmed/30577422 http://dx.doi.org/10.3390/proteomes7010001

Ejemplares similares

The Constitutive Extracellular Protein Release by Acute Myeloid Leukemia Cells—A Proteomic Study of Patient Heterogeneity and Its Modulation by Mesenchymal Stromal Cells
por: Aasebø, Elise, et al.
Publicado: (2021)

Selecting Sample Preparation Workflows for Mass Spectrometry-Based Proteomic and Phosphoproteomic Analysis of Patient Samples with Acute Myeloid Leukemia
por: Hernandez-Valladares, Maria, et al.
Publicado: (2016)

The Extracellular Bone Marrow Microenvironment—A Proteomic Comparison of Constitutive Protein Release by In Vitro Cultured Osteoblasts and Mesenchymal Stem Cells
por: Aasebø, Elise, et al.
Publicado: (2020)

Patient Heterogeneity in Acute Myeloid Leukemia: Leukemic Cell Communication by Release of Soluble Mediators and Its Effects on Mesenchymal Stem Cells
por: Aasebø, Elise, et al.
Publicado: (2021)

Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation
por: Hernandez-Valladares, Maria, et al.
Publicado: (2020)

Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients
por: Hernandez-Valladares, Maria, et al.
Publicado: (2016)

The Progression of Acute Myeloid Leukemia from First Diagnosis to Chemoresistant Relapse: A Comparison of Proteomic and Phosphoproteomic Profiles
por: Aasebø, Elise, et al.
Publicado: (2020)

Proteomic Studies of Primary Acute Myeloid Leukemia Cells Derived from Patients Before and during Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid and Valproic Acid
por: Hernandez-Valladares, Maria, et al.
Publicado: (2021)

Proteomic Comparison of Bone Marrow Derived Osteoblasts and Mesenchymal Stem Cells
por: Aasebø, Elise, et al.
Publicado: (2021)

Global Cell Proteome Profiling, Phospho-signaling and Quantitative  Proteomics for Identification of New Biomarkers in Acute Myeloid  Leukemia Patients
por: Aasebø, Elise, et al.
Publicado: (2016)

The Capacity of Long-Term In Vitro Proliferation of Acute Myeloid Leukemia Cells Supported Only by Exogenous Cytokines Is Associated with a Patient Subset with Adverse Outcome
por: Brenner, Annette K., et al.
Publicado: (2019)

Preservation Method and Phosphate Buffered Saline Washing Affect the Acute Myeloid Leukemia Proteome
por: Wangen, Rebecca, et al.
Publicado: (2018)

Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia
por: Aasebø, Elise, et al.
Publicado: (2020)

The Implementation of Mass Spectrometry-Based Proteomics Workflows in Clinical Routines of Acute Myeloid Leukemia: Applicability and Perspectives
por: Hernandez-Valladares, Maria, et al.
Publicado: (2020)

Effects of the Autophagy-Inhibiting Agent Chloroquine on Acute Myeloid Leukemia Cells; Characterization of Patient Heterogeneity
por: Grønningsæter, Ida Sofie, et al.
Publicado: (2021)

Vacuolar ATPase Is a Possible Therapeutic Target in Acute Myeloid Leukemia: Focus on Patient Heterogeneity and Treatment Toxicity
por: Bartaula-Brevik, Sushma, et al.
Publicado: (2023)

Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells
por: Nepstad, Ina, et al.
Publicado: (2019)

High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype
por: Reikvam, Håkon, et al.
Publicado: (2019)

S100 Proteins in Acute Myeloid Leukemia()()
por: Brenner, Annette K., et al.
Publicado: (2018)

Mass Spectrometry-Based Proteomics Workflows in Cancer Research: The Relevance of Choosing the Right Steps
por: Carrillo-Rodriguez, Paula, et al.
Publicado: (2023)

Effects of Blood Contamination and the Rostro-Caudal Gradient on the Human Cerebrospinal Fluid Proteome
por: Aasebø, Elise, et al.
Publicado: (2014)

Targeting Cellular Metabolism in Acute Myeloid Leukemia and the Role of Patient Heterogeneity
por: Grønningsæter, Ida Sofie, et al.
Publicado: (2020)

Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia
por: Haaland, Ingvild, et al.
Publicado: (2014)

Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia
por: Bruserud, Øystein, et al.
Publicado: (2022)

Iodinin (1,6-Dihydroxyphenazine 5,10-Dioxide) from Streptosporangium sp. Induces Apoptosis Selectively in Myeloid Leukemia Cell Lines and Patient Cells
por: Myhren, Lene E., et al.
Publicado: (2013)

Clinical proteomics of myeloid leukemia
por: Hjelle, Sigrun M, et al.
Publicado: (2010)

A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators
por: Brenner, Annette K., et al.
Publicado: (2016)

Mesenchymal Stem Cells Support Survival and Proliferation of Primary Human Acute Myeloid Leukemia Cells through Heterogeneous Molecular Mechanisms
por: Brenner, Annette K., et al.
Publicado: (2017)

Functional Toll-Like Receptors (TLRs) Are Expressed by a Majority of Primary Human Acute Myeloid Leukemia Cells and Inducibility of the TLR Signaling Pathway Is Associated with a More Favorable Phenotype
por: Brenner, Annette K., et al.
Publicado: (2019)

The Possible Importance of β3 Integrins for Leukemogenesis and Chemoresistance in Acute Myeloid Leukemia
por: Johansen, Silje, et al.
Publicado: (2018)

Comparing Efficiency of Lysis Buffer Solutions and Sample Preparation Methods for Liquid Chromatography–Mass Spectrometry Analysis of Human Cells and Plasma
por: Neset, Lasse, et al.
Publicado: (2022)

Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms
por: Brenner, Annette K., et al.
Publicado: (2014)

CDC25 Inhibition in Acute Myeloid Leukemia–A Study of Patient Heterogeneity and the Effects of Different Inhibitors
por: Brenner, Annette K., et al.
Publicado: (2017)

Resistance to the Antiproliferative In Vitro Effect of PI3K-Akt-mTOR Inhibition in Primary Human Acute Myeloid Leukemia Cells Is Associated with Altered Cell Metabolism
por: Nepstad, Ina, et al.
Publicado: (2018)

Casein Kinase 2 (CK2): A Possible Therapeutic Target in Acute Myeloid Leukemia
por: Bruserud, Øystein, et al.
Publicado: (2023)

The Systemic Profile of Soluble Immune Mediators in Patients with Myelodysplastic Syndromes
por: Kittang, Astrid Olsnes, et al.
Publicado: (2016)

Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes
por: Oftedal, Linn, et al.
Publicado: (2010)

Therapeutic Use of Valproic Acid and All-Trans Retinoic Acid in Acute Myeloid Leukemia—Literature Review and Discussion of Possible Use in Relapse after Allogeneic Stem Cell Transplantation
por: Bruserud, Øystein, et al.
Publicado: (2021)

compomics-utilities: an open-source Java library for computational proteomics
por: Barsnes, Harald, et al.
Publicado: (2011)

Clonal Heterogeneity Reflected by PI3K-AKT-mTOR Signaling in Human Acute Myeloid Leukemia Cells and Its Association with Adverse Prognosis
por: Nepstad, Ina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3f5sp9616kufc4iikdcrpuqqt8