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New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral ant...

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Detalles Bibliográficos
Autores principales: Arcadi, Francesca Antonia, Portaro, Simona, Giorgianni, Roberto, Naro, Antonino, Casella, Carmela, Genovese, Carmelo, Marino, Silvia, Calabrò, Rocco Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473779/
https://www.ncbi.nlm.nih.gov/pubmed/30884868
http://dx.doi.org/10.3390/medicina55030071
Descripción
Sumario:Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation.