New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral ant...

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Autores principales: Arcadi, Francesca Antonia, Portaro, Simona, Giorgianni, Roberto, Naro, Antonino, Casella, Carmela, Genovese, Carmelo, Marino, Silvia, Calabrò, Rocco Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473779/
https://www.ncbi.nlm.nih.gov/pubmed/30884868
http://dx.doi.org/10.3390/medicina55030071
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author Arcadi, Francesca Antonia
Portaro, Simona
Giorgianni, Roberto
Naro, Antonino
Casella, Carmela
Genovese, Carmelo
Marino, Silvia
Calabrò, Rocco Salvatore
author_facet Arcadi, Francesca Antonia
Portaro, Simona
Giorgianni, Roberto
Naro, Antonino
Casella, Carmela
Genovese, Carmelo
Marino, Silvia
Calabrò, Rocco Salvatore
author_sort Arcadi, Francesca Antonia
collection PubMed
description Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation.
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spelling pubmed-64737792019-05-02 New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report Arcadi, Francesca Antonia Portaro, Simona Giorgianni, Roberto Naro, Antonino Casella, Carmela Genovese, Carmelo Marino, Silvia Calabrò, Rocco Salvatore Medicina (Kaunas) Case Report Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation. MDPI 2019-03-17 /pmc/articles/PMC6473779/ /pubmed/30884868 http://dx.doi.org/10.3390/medicina55030071 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Arcadi, Francesca Antonia
Portaro, Simona
Giorgianni, Roberto
Naro, Antonino
Casella, Carmela
Genovese, Carmelo
Marino, Silvia
Calabrò, Rocco Salvatore
New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_full New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_fullStr New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_full_unstemmed New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_short New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_sort new versus old oral anticoagulants: how can we set the scale needle? considerations on a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473779/
https://www.ncbi.nlm.nih.gov/pubmed/30884868
http://dx.doi.org/10.3390/medicina55030071
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