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Regulation of Actin Dynamics in the C. elegans Somatic Gonad
The reproductive system of the hermaphroditic nematode C. elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473838/ https://www.ncbi.nlm.nih.gov/pubmed/30897735 http://dx.doi.org/10.3390/jdb7010006 |
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author | Kelley, Charlotte A. Cram, Erin J |
author_facet | Kelley, Charlotte A. Cram, Erin J |
author_sort | Kelley, Charlotte A. |
collection | PubMed |
description | The reproductive system of the hermaphroditic nematode C. elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embryo into the uterus. Contraction is driven by acto-myosin contraction and relies on the development and maintenance of specialized acto-myosin networks in each cell type. Study of this system has revealed insights into the regulation of acto-myosin network assembly and contractility in vivo. |
format | Online Article Text |
id | pubmed-6473838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64738382019-04-29 Regulation of Actin Dynamics in the C. elegans Somatic Gonad Kelley, Charlotte A. Cram, Erin J J Dev Biol Review The reproductive system of the hermaphroditic nematode C. elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embryo into the uterus. Contraction is driven by acto-myosin contraction and relies on the development and maintenance of specialized acto-myosin networks in each cell type. Study of this system has revealed insights into the regulation of acto-myosin network assembly and contractility in vivo. MDPI 2019-03-20 /pmc/articles/PMC6473838/ /pubmed/30897735 http://dx.doi.org/10.3390/jdb7010006 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kelley, Charlotte A. Cram, Erin J Regulation of Actin Dynamics in the C. elegans Somatic Gonad |
title | Regulation of Actin Dynamics in the C. elegans Somatic Gonad |
title_full | Regulation of Actin Dynamics in the C. elegans Somatic Gonad |
title_fullStr | Regulation of Actin Dynamics in the C. elegans Somatic Gonad |
title_full_unstemmed | Regulation of Actin Dynamics in the C. elegans Somatic Gonad |
title_short | Regulation of Actin Dynamics in the C. elegans Somatic Gonad |
title_sort | regulation of actin dynamics in the c. elegans somatic gonad |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473838/ https://www.ncbi.nlm.nih.gov/pubmed/30897735 http://dx.doi.org/10.3390/jdb7010006 |
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