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Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

BACKGROUND: Staphylococcus aureus is the most frequent and fatal cause of left-sided infective endocarditis (IE). New treatment strategies are needed to improve the outcome. S. aureus coagulase promotes clot and fibrin formation. We hypothesized that dabigatran, could reduce valve vegetations and in...

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Detalles Bibliográficos
Autores principales:	Lerche, Christian J., Christophersen, Lars J., Goetze, Jens Peter, Nielsen, Pia R., Thomsen, Kim, Enevold, Christian, Høiby, Niels, Jensen, Peter Ø., Bundgaard, Henning, Moser, Claus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474597/ https://www.ncbi.nlm.nih.gov/pubmed/31002679 http://dx.doi.org/10.1371/journal.pone.0215333

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