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Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway
Tubule-interstitial injury (TII) is a critical step in the progression of renal disease. It has been proposed that changes in proximal tubule (PT) albumin endocytosis plays an important role in the development of TII. Some reports have shown protective effects of lithium on kidney injury animal mode...
Autores principales: | Teixeira, Douglas E., Peruchetti, Diogo B., Silva, Leandro S., Silva-Aguiar, Rodrigo P., Oquendo, Morgana B., Silva-Filho, João Luiz, Takiya, Christina M., Leal-Cardoso, José Henrique, Pinheiro, Ana Acacia S., Caruso-Neves, Celso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474631/ https://www.ncbi.nlm.nih.gov/pubmed/31002704 http://dx.doi.org/10.1371/journal.pone.0215871 |
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