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Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo
RAS genes are the most commonly mutated oncogenes in human cancers. Despite tremendous efforts over the past several decades, however, RAS-specific inhibitors remain elusive. Thus, targeting RAS remains a highly sought after goal of cancer research. Previously, we reported a new approach to inhibit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474814/ https://www.ncbi.nlm.nih.gov/pubmed/30573767 http://dx.doi.org/10.1038/s41388-018-0636-y |