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SMURF1-mediated ubiquitination of ARHGAP26 promotes ovarian cancer cell invasion and migration

Rho GTPase-activating protein 26 (ARHGAP26) is a negative regulator of the Rho family that converts the small GTP-binding protein RhoA (GTP-RhoA) to its inactive GDP-bound form and is a putative tumor suppressor gene associated with cell growth and migration. Here, the involvement of ARHGAP26 in ova...

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Detalles Bibliográficos
Autores principales: Chen, Xuri, Chen, Shaoyun, Li, Yao, Gao, Yanling, Huang, Shuying, Li, Hongping, Zhu, Yuanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474862/
https://www.ncbi.nlm.nih.gov/pubmed/31004081
http://dx.doi.org/10.1038/s12276-019-0236-0