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Potent and PPARα-independent anti-proliferative action of the hypolipidemic drug fenofibrate in VEGF-dependent angiosarcomas in vitro

Angiosarcomas are highly aggressive tumors of endothelial origin, which carry a poor prognosis. Fenofibrate is a hypolipidemic drug, which acts by activating the transcription factor PPARα. It has also been widely reported to have ‘anti-cancer’ activity. The current study investigated its effect in...

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Detalles Bibliográficos
Autores principales:	Majeed, Yasser, Upadhyay, Rohit, Alhousseiny, Sara, Taha, Tarek, Musthak, Adham, Shaheen, Yanal, Jameel, Mohtashim, Triggle, Chris R., Ding, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474884/ https://www.ncbi.nlm.nih.gov/pubmed/31004117 http://dx.doi.org/10.1038/s41598-019-42838-y

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