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Dose escalation of preoperative short-course radiotherapy followed by neoadjuvant chemotherapy in locally advanced rectal cancer: protocol for an open-label, single-centre, phase I clinical trial
INTRODUCTION: Preoperative radiotherapy followed by total mesorectal excision with adjuvant chemotherapy has been recommended as the preferred treatment method for locally advanced rectal cancer (LARC). Similar rates of local control, survival and toxicity were observed in preoperative long-course c...
Autores principales: | Zhang, Meng-xia, Li, Xiao-bo, Guan, Bing-jie, Guan, Guo-xian, Lin, Xiao-yan, Wu, Xiao-dong, Chi, Pan, Xu, Ben-hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475145/ https://www.ncbi.nlm.nih.gov/pubmed/30904869 http://dx.doi.org/10.1136/bmjopen-2018-025944 |
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