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Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties
Phase separation of multivalent protein and RNA molecules underlies the biogenesis of biomolecular condensates such as membraneless organelles. In vivo, these condensates encompass hundreds of distinct types of molecules that typically organize into multilayered structures supporting the differentia...
Autores principales: | Boeynaems, Steven, Holehouse, Alex S., Weinhardt, Venera, Kovacs, Denes, Van Lindt, Joris, Larabell, Carolyn, Van Den Bosch, Ludo, Das, Rhiju, Tompa, Peter S., Pappu, Rohit V., Gitler, Aaron D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475405/ https://www.ncbi.nlm.nih.gov/pubmed/30926670 http://dx.doi.org/10.1073/pnas.1821038116 |
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