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Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties

Phase separation of multivalent protein and RNA molecules underlies the biogenesis of biomolecular condensates such as membraneless organelles. In vivo, these condensates encompass hundreds of distinct types of molecules that typically organize into multilayered structures supporting the differentia...

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Detalles Bibliográficos
Autores principales: Boeynaems, Steven, Holehouse, Alex S., Weinhardt, Venera, Kovacs, Denes, Van Lindt, Joris, Larabell, Carolyn, Van Den Bosch, Ludo, Das, Rhiju, Tompa, Peter S., Pappu, Rohit V., Gitler, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475405/
https://www.ncbi.nlm.nih.gov/pubmed/30926670
http://dx.doi.org/10.1073/pnas.1821038116

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