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Chemical synthesis rewriting of a bacterial genome to achieve design flexibility and biological functionality

Understanding how to program biological functions into artificial DNA sequences remains a key challenge in synthetic genomics. Here, we report the chemical synthesis and testing of Caulobacter ethensis-2.0 (C. eth-2.0), a rewritten bacterial genome composed of the most fundamental functions of a bac...

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Detalles Bibliográficos
Autores principales:	Venetz, Jonathan E., Del Medico, Luca, Wölfle, Alexander, Schächle, Philipp, Bucher, Yves, Appert, Donat, Tschan, Flavia, Flores-Tinoco, Carlos E., van Kooten, Mariëlle, Guennoun, Rym, Deutsch, Samuel, Christen, Matthias, Christen, Beat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475421/ https://www.ncbi.nlm.nih.gov/pubmed/30936302 http://dx.doi.org/10.1073/pnas.1818259116

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