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Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation

Osteochondritis dissecans (OCD) has been recognized for over 100 years yet still poses treatment challenges owing to both the avascular nature of articular cartilage and the inability to generate hyaline cartilage. The knee is most commonly involved, and without repair, patients have chronic knee pa...

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Autores principales: Gwosdz, James, Rosinski, Alexander, Chakrabarti, Moyukh, Woodall, Brittany M., Elena, Nicholas, McGahan, Patrick J., Chen, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475622/
https://www.ncbi.nlm.nih.gov/pubmed/31016129
http://dx.doi.org/10.1016/j.eats.2018.11.008
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author Gwosdz, James
Rosinski, Alexander
Chakrabarti, Moyukh
Woodall, Brittany M.
Elena, Nicholas
McGahan, Patrick J.
Chen, James L.
author_facet Gwosdz, James
Rosinski, Alexander
Chakrabarti, Moyukh
Woodall, Brittany M.
Elena, Nicholas
McGahan, Patrick J.
Chen, James L.
author_sort Gwosdz, James
collection PubMed
description Osteochondritis dissecans (OCD) has been recognized for over 100 years yet still poses treatment challenges owing to both the avascular nature of articular cartilage and the inability to generate hyaline cartilage. The knee is most commonly involved, and without repair, patients have chronic knee pain, loose bodies, and early-onset osteoarthritis. There are a number of surgical techniques for repairing OCD, some of which are still being refined. Currently, common procedures used to treat OCD lesions include microfracture, autologous chondrocyte implantation, osteochondral autograft transplantation, and osteochondral allograft transplantation. In this Technical Note, we describe osteochondral allograft transplantation with the addition of platelet-rich plasma and graft-recipient microfracture. We believe the micropores augment the osteoconductive and osteoinductive properties of the allograft and aid in the incorporation of the allograft plug by improving angiogenesis, enhancing clot formation in the allograft, and providing a homogeneous environment for remodeling.
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spelling pubmed-64756222019-04-23 Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation Gwosdz, James Rosinski, Alexander Chakrabarti, Moyukh Woodall, Brittany M. Elena, Nicholas McGahan, Patrick J. Chen, James L. Arthrosc Tech Technical Note Osteochondritis dissecans (OCD) has been recognized for over 100 years yet still poses treatment challenges owing to both the avascular nature of articular cartilage and the inability to generate hyaline cartilage. The knee is most commonly involved, and without repair, patients have chronic knee pain, loose bodies, and early-onset osteoarthritis. There are a number of surgical techniques for repairing OCD, some of which are still being refined. Currently, common procedures used to treat OCD lesions include microfracture, autologous chondrocyte implantation, osteochondral autograft transplantation, and osteochondral allograft transplantation. In this Technical Note, we describe osteochondral allograft transplantation with the addition of platelet-rich plasma and graft-recipient microfracture. We believe the micropores augment the osteoconductive and osteoinductive properties of the allograft and aid in the incorporation of the allograft plug by improving angiogenesis, enhancing clot formation in the allograft, and providing a homogeneous environment for remodeling. Elsevier 2019-02-25 /pmc/articles/PMC6475622/ /pubmed/31016129 http://dx.doi.org/10.1016/j.eats.2018.11.008 Text en © 2019 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Gwosdz, James
Rosinski, Alexander
Chakrabarti, Moyukh
Woodall, Brittany M.
Elena, Nicholas
McGahan, Patrick J.
Chen, James L.
Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation
title Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation
title_full Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation
title_fullStr Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation
title_full_unstemmed Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation
title_short Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation
title_sort osteochondral allograft transplantation of the medial femoral condyle with orthobiologic augmentation and graft-recipient microfracture preparation
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475622/
https://www.ncbi.nlm.nih.gov/pubmed/31016129
http://dx.doi.org/10.1016/j.eats.2018.11.008
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