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Sir2D, a Sirtuin family protein, regulates adenylate cyclase A expression through interaction with the MybB transcription factor early in Dictyostelium development upon starvation

Sirtuin interacts with many regulatory proteins involved in energy homeostasis, DNA repair, cell survival, and lifespan extension. We investigated the functional roles of Sir2D during early Dictyostelium development upon starvation. We found that ectopic expression of Sir2D accelerated development a...

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Detalles Bibliográficos
Autores principales: Taniura, Hideo, Soeda, Shuhei, Ohta, Tomoko, Oki, Maya, Tsuboi, Risako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475656/
https://www.ncbi.nlm.nih.gov/pubmed/31016257
http://dx.doi.org/10.1016/j.heliyon.2019.e01301