Bp-Bs, a Novel T-cell Engaging Bispecific Antibody with Biparatopic Her2 Binding, Has Potent Anti-tumor Activities

Patients with Human epidermal growth factor receptor type 2 (Her2) overexpression are associated with aggressive tumor growth and poor clinical outcomes. Bispecific antibodies targeting Her2 have recently exhibited potent effects on Her2 signal inhibition. In this study, a novel biparatopic anti-Her...

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Detalles Bibliográficos
Autores principales: Liu, Jiayu, Wu, Xiaoqiong, Lin, Limin, Pan, Haitao, Wang, Yanlan, Li, Yumei, Zhao, Yining, Wang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475711/
https://www.ncbi.nlm.nih.gov/pubmed/31020038
http://dx.doi.org/10.1016/j.omto.2019.03.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475711/
https://www.ncbi.nlm.nih.gov/pubmed/31020038
http://dx.doi.org/10.1016/j.omto.2019.03.009

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