Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells

Herpes simplex virus 1 (HSV-1) establishes latency in both peripheral nerve ganglia and the central nervous system (CNS). The outcomes of acute and latent infections in these different anatomic sites appear to be distinct. It is becoming clear that many of the existing culture models using animal pr...

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Detalles Bibliográficos
Autores principales: D’Aiuto, Leonardo, Bloom, David C., Naciri, Jennifer N., Smith, Adam, Edwards, Terri G., McClain, Lora, Callio, Jason A., Jessup, Morgan, Wood, Joel, Chowdari, Kodavali, Demers, Matthew, Abrahamson, Eric E., Ikonomovic, Milos D., Viggiano, Luigi, De Zio, Roberta, Watkins, Simon, Kinchington, Paul R., Nimgaonkar, Vishwajit L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475775/
https://www.ncbi.nlm.nih.gov/pubmed/30787148
http://dx.doi.org/10.1128/JVI.00111-19

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