Structure of the Anti-C60 Fullerene Antibody Fab Fragment: Structural Determinants of Fullerene Binding

The structure of the anti-C(60) fullerene antibody Fab fragment (FabC(60)) was solved by X-ray crystallography. The computer-aided docking of C(60) into the antigen-binding pocket of FabC(60) showed that binding of C(60) to FabC(60) is governed by the enthalpy and entropy; namely, by π-π stacking in...

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Detalles Bibliográficos
Autores principales: Osipov, E. M., Hendrickson, O. D., Tikhonova, T. V., Zherdev, A. V., Solopova, O. N., Sveshnikov, P. G., Dzantiev, B. B., Popov, V. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475864/
https://www.ncbi.nlm.nih.gov/pubmed/31024749

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