Cargando…

Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF-κB/TNF-α Signaling Pathway

Aging is a risk factor for cardiovascular disease, and there is no effective therapeutic approach to alleviate this condition. NF-κB and TNF-α have been implicated in the activation of the aging process, but the signaling molecules responsible for the inactivation of NF-κB and TNF-α remain unknown....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Bao, Zhang, Lulu, Liang, Chun, Liu, Bin, Pan, Xiangbin, Wang, Yanli, Zhang, Yuqing, Zhang, Yu, Xie, Wenping, Yan, Bing, Liu, Feng, Yip, Hon-Kan, Yu, Xi-yong, Li, Yangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476062/
https://www.ncbi.nlm.nih.gov/pubmed/31089420
http://dx.doi.org/10.1155/2019/9739258