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Mutational load causes stochastic evolutionary outcomes in acute RNA viral infection
Mutational load is known to be of importance for the evolution of RNA viruses, the combination of a high mutation rate and large population size leading to an accumulation of deleterious mutations. However, while the effects of mutational load on global viral populations have been considered, its qu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476161/ https://www.ncbi.nlm.nih.gov/pubmed/31024738 http://dx.doi.org/10.1093/ve/vez008 |