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Mutational load causes stochastic evolutionary outcomes in acute RNA viral infection

Mutational load is known to be of importance for the evolution of RNA viruses, the combination of a high mutation rate and large population size leading to an accumulation of deleterious mutations. However, while the effects of mutational load on global viral populations have been considered, its qu...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Abbasi, Ali B, Illingworth, Christopher J R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476161/
https://www.ncbi.nlm.nih.gov/pubmed/31024738
http://dx.doi.org/10.1093/ve/vez008