Cargando…

CD40L inhibits cell growth of THP-1 cells by suppressing the PI3K/Akt pathway

INTRODUCTION: Acute myeloid leukemia (AML), the hematological malignant tumor with high mortality, is still difficult to treat. CD40L is a type II transmembrane protein, which has been reported to have the potential to inhibit growth of some cancer cells. MATERIALS AND METHODS: In order to determine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Zhongxin, Chen, Qi, Ren, Mingqiang, Tian, Zuguo, Gong, Yuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476227/ https://www.ncbi.nlm.nih.gov/pubmed/31114244 http://dx.doi.org/10.2147/OTT.S175347

Ejemplares similares

CD40L inhibits cell growth of THP-1 cells by suppressing the PI3K/Akt pathway [Corrigendum]
por: Feng, Z, et al.
Publicado: (2019)

Raised CD40L expression attenuates drug resistance in Adriamycin-resistant THP-1 cells
por: Feng, Zhongxin, et al.
Publicado: (2020)

Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
por: TIAN, FENG, et al.
Publicado: (2015)

Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
por: Tian, Feng, et al.
Publicado: (2023)

Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells
por: Kim, Ju-Young, et al.
Publicado: (2010)

Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway
por: Huang, Xiaoyan, et al.
Publicado: (2016)

A Biodegradable Mg-Based Alloy Inhibited the Inflammatory Response of THP-1 Cell-Derived Macrophages Through the TRPM7–PI3K–AKT1 Signaling Axis
por: Jin, Liang, et al.
Publicado: (2019)

Role of PI3K/Akt signaling in memory CD8 T cell differentiation
por: Kim, Eui Ho, et al.
Publicado: (2013)

Overexpression of Rab40b Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway
por: Shi, Li-Wei, et al.
Publicado: (2020)

Knockdown of Ski decreases osteosarcoma cell proliferation and migration by suppressing the PI3K/Akt signaling pathway
por: Zhao, Xin, et al.
Publicado: (2019)

Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells
por: Quan, Juan-Hua, et al.
Publicado: (2015)

The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway
por: Tlili, Hajer, et al.
Publicado: (2021)

Effect of PI3K/Akt Signaling Pathway on PRAS40Thr246 Phosphorylation in Gastric Cancer Cells
por: LU, Yizhuo, et al.
Publicado: (2019)

Role of PI3K/Akt pathway in Benzidine-induced proliferation in SV-40 immortalized human uroepithelial cell
por: Ding, Demao, et al.
Publicado: (2019)

Eriodictyol Suppresses Gastric Cancer Cells via Inhibition of PI3K/AKT Pathway
por: Shan, Hui, et al.
Publicado: (2022)

Anti-tumor activity of Shikonin against afatinib resistant non-small cell lung cancer via negative regulation of PI3K/Akt signaling pathway
por: Li, Baiying, et al.
Publicado: (2018)

OX40L induces helper T cell differentiation during cell immunity of asthma through PI3K/AKT and P38 MAPK signaling pathway
por: Huang, Li, et al.
Publicado: (2018)

ROS-Dependent Activation of Autophagy through the PI3K/Akt/mTOR Pathway Is Induced by Hydroxysafflor Yellow A-Sonodynamic Therapy in THP-1 Macrophages
por: Jiang, Yueqing, et al.
Publicado: (2017)

Cinnamaldehyde Inhibits the Function of Osteosarcoma by Suppressing the Wnt/β-Catenin and PI3K/Akt Signaling Pathways
por: Huang, Yanran, et al.
Publicado: (2020)

Fangchinoline induces gallbladder cancer cell apoptosis by suppressing PI3K/Akt/XIAP axis
por: Li, Jiandong, et al.
Publicado: (2022)

Astragalus Polysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways
por: Cao, Yuan, et al.
Publicado: (2014)

Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals
Publicado: (1995)

Anhydroicaritin suppresses tumor progression via the PI3K/AKT signaling pathway in hepatocellular carcinoma
por: Wang, Houhong, et al.
Publicado: (2023)

CD40–CD40L in Neurological Disease
por: Ots, Heather D., et al.
Publicado: (2022)

Soluble CD40 ligand inhibits the growth of non-Hodgkin's lymphoma cells through the JNK signaling pathway
por: Feng, Zhongxin, et al.
Publicado: (2021)

High Density Lipoprotein Protects Mesenchymal Stem Cells from Oxidative Stress-Induced Apoptosis via Activation of the PI3K/Akt Pathway and Suppression of Reactive Oxygen Species
por: Xu, Jianfeng, et al.
Publicado: (2012)

Long non-coding RNA FER1L4 inhibits cell proliferation and metastasis through regulation of the PI3K/AKT signaling pathway in lung cancer cells
por: Gao, Xuejin, et al.
Publicado: (2019)

Preeclampsia serum upregulates CD40/CD40L expression and induces apoptosis in human umbilical cord endothelial cells
por: Wu, Chun-feng, et al.
Publicado: (2012)

Hyperoside suppresses BMP-7-dependent PI3K/AKT pathway in human hepatocellular carcinoma cells
por: Wei, Shuang, et al.
Publicado: (2021)

PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway
por: Zheng, Zhewen, et al.
Publicado: (2022)

HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway
por: Wang, Haowei, et al.
Publicado: (2022)

Acetate decreases PVR/CD155 expression via PI3K/AKT pathway in cancer cells
por: Tran, Na Ly, et al.
Publicado: (2021)

DOK7 Inhibits Cell Proliferation, Migration, and Invasion of Breast Cancer via the PI3K/PTEN/AKT Pathway
por: Yue, Changli, et al.
Publicado: (2021)

Mycoplasma Suppression of THP-1 Cell TLR Responses Is Corrected with Antibiotics
por: Zakharova, Ekaterina, et al.
Publicado: (2010)

Embryonic stem cell microenvironment suppresses the malignancy of cutaneous melanoma cells by down‐regulating PI3K/AKT pathway
por: Wang, Chenjie, et al.
Publicado: (2019)

LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway
por: Liu, Yan, et al.
Publicado: (2020)

Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
por: Lacy, Michael, et al.
Publicado: (2021)

Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway
por: Zhang, Yong, et al.
Publicado: (2020)

Pterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway
por: Tong, Chenhao, et al.
Publicado: (2021)

Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway
por: Xiang, Ming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p986up2j71gd9eis9m0s00bcjg