Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides

Objectives: Most DAMPs in inflammatory diseases are TLR2- and TLR4-ligands and according to the current concept, repeated stimuli would result in tolerance. Aims of the study were to verify this assumption, to investigate whether epigenetic effectors are involved and to explore the situation in rheu...

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Detalles Bibliográficos
Autores principales: Neidhart, Michel, Pajak, Agnieszka, Laskari, Katerina, Riksen, Niels P., Joosten, Leo A. B., Netea, Mihai G., Lutgens, Esther, Stroes, Eric S. G., Ciurea, Adrian, Distler, Oliver, Grigorian, Mariam, Karouzakis, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476283/
https://www.ncbi.nlm.nih.gov/pubmed/31037071
http://dx.doi.org/10.3389/fimmu.2019.00791

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